Autoimmunity and Diabetes

Diabetes and Autoimmunity

Gestational Diabetes and Thyroid Autoimmunity

Background. About 10% of pregnancies are complicated by previously unknown impairment of glucose metabolism, which is defined as gestational diabetes. There are little data available on prevalence of thyroid disorders in patients affected by gestational diabetes, and about their postgestational thyroid function and autoimmunity. We therefore investigated pancreatic and thyroid autoimmunity in g...

Type 1 Diabetes and Autoimmunity

Type 1 diabetes (T1D) is an organ-specific autoimmune disease caused by the autoimmune response against pancreatic β cells. T1D is often complicated with other autoimmune diseases, and anti-islet autoantibodies precede the clinical onset of disease. The most common coexisting organ-specific autoimmune disease in patients with T1D is autoimmune thyroid disease, and its frequency is estimated at ...

Tolerance and Autoimmunity in Type 1 Diabetes

Echovirus Epidemics, Autoimmunity, and Type 1 Diabetes

Type 1 diabetes mellitus [T1D] results from the autoimmune destruction of insulinproducing beta cells triggered by environmental factors (Hyoty & Taylor, 2002; Jun & Yoon, 2003). Genetic predisposition accounts for 36-50% of disease susceptibility as demonstrated in monozygotic twin studies (Barnett et al., 1981; Hemminki et al., 2010; Redondo et al., 2001). Differences in the incidence of T1D ...